Cardiovascular Clinical Trials

Cardiovascular clinical trials are research studies through which improvements in the prevention, detection and treatment of heart disease are tested.

Clinical trials evaluate new drugs, devices and procedures that are not yet available to the public. By participating in a clinical trial, you may have early access to these treatments before they become widely available, and you can directly contribute to the advancement of medical research.

Numerous studies have demonstrated better clinical outcomes for clinical trial participants irrespective of treatment allocation (active intervention or control group) because of the expert monitoring and treatment they receive as part of the clinical trial.

If you are interested in finding out more about participating in any of our current trials, please contact us at ISLHD-cardiacresearch@health.nsw.gov.au or (02) 4253 4908.

Current trials

Illawarra Heart Health Centre - Cardiovascular Clinical Trials (intervention)

Trial Name

Full Title

Principal Investigator

Status

EASY-AS

A trial of early valve replacement in severe asymptomatic aortic stenosis.

Dr Danson

Open to recruitment

GOAL-ASIA

The GOAL-ASIA study aims to engage and empower patients to know their cholesterol levels, understand the medications they're on to lower it, and to help them reach their goals by knowing their targets.

A/Prof Lee

Open to recruitment

PARTICIPATE Partnering remote monitoring of Implanted cardiac devices with intelligent patient engagement A/Prof Lee Open to recruitment
RELEVANT LV  Resolution of left ventricular thrombus with different snit coagulation strategies Dr Moragues Open to recruitment
PROTECT-ICD  Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias following Acute Myocardial Infarction A/Prof Lee Open to recruitment

Cardiovascular Clinical Trials (Drug)

Trial Name

Full Title

Principal Investigator

Status

ATHENA

Ziltivekimab (anti-inflammatory monoclonal antibody) versus placebo in patients with cardiovascular disease, renal impairment and raised hs-CRP. CV outcome study Monthly injection

A/Prof Lee

Recruitment commencing June 2024

ARTEMIS 

Effects of Ziltivekimab Vs placebo on cardiovascular outcomes in patients with Acute Myocardial Infarction

A/Prof Lee

Recruitment commencing June 2024

Observational Trials

Trial Name

Full Title

Principal Investigator

Status

POSEIDEN ASCVD and HF Prevalence of systemic inflammation in patients with atherosclerotic cardiovascular disease and heart failure A/Prof Lee Recruitment commencing June 2024